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A = consistent, good-quality patient-oriented evidence; B = inconsistent or limited-quality patient-oriented evidence; C = consensus, disease-oriented evidence, usual practice, expert opinion, or case series.

The use of atypical antipsychotics such as quetiapine and olanzapine is increasing.

Anticholinergic effects are especially prominent with weaker-binding first-generation antipsychotics, as well as with the second-generation antipsychotic clozapine.

All antipsychotic medications are associated with an increased likelihood of sedation, sexual dysfunction, postural hypotension, cardiac arrhythmia, and sudden cardiac death.

Deciding which treatment or combination of treatments to prescribe depends on a careful interview and assessment of the patient's goals and level of pathology.

The outcome of treatment is determined by several factors, including the following: Patients with significant discomfort from their anxiety can benefit from emergency anxiolytic treatment, primarily with a benzodiazepine.

Antidepressant agents are the drugs of choice in the treatment of anxiety disorders, particularly the newer agents, which have a safer adverse effect profile and higher ease of use than the older tricyclic antidepressants (TCAs), such as selective serotonin reuptake inhibitors (SSRIs).

Antidepressants that are not FDA-approved for the treatment of a given anxiety disorder, such as nefazodone and mirtazapine, still may be beneficial.

They differ in that the so called atypicals are non-neuroleptics and interact with both serotonin and Dopamine receptos, while the typicals on the antipsychotic drug used, generally speaking drug-drug interaction usually occurs with antipsychotics, antibiotics and anticoagulants (blood thinners), so caution is advised with the use of multiple drugs any how, as far as I know there is no significant interaction between benadryl (diphenhydramine) and zoloft for example, but not sure what medicine you're referring to, kindly run it by your physician ...

In many cases, these medicines are used for “off-label” indications and this is a worrying trend given their potential for significant metabolic adverse effects.

Antipsychotics are indicated for the treatment of schizophrenia and related disorders and in some circumstances to treat the behavioural and psychological symptoms associated with dementia (risperidone only).

As with all prescription medication, the benefits and risks are an important part of the discussion between doc and pt.

That prescription drugs are now being advertised to pts, in order to manipulate the physicians prescribing practices, is just one more abomination in the fld. Read more See 1 more doctor answer These are medications used among other things to treat psychosis.